Substrate-independence implies the Turing principle. Or maybe the opposite: the Turing principle implies substrate-independence. Or maybe it’s just the same thing conceptualized differently.
If my second postulate is true, that means substrate-independence can be only realized by beings which can use symbols. That is, humans. (10-2g2e Universality of the laws of physics depends on the existence of universal explainers — people)develop
10-2g1f2b The brain and symbols evolved reflexively to enhance communication to deal with cultural and sexual selectional pressures.
10-2g3d1 Humans do stupid things because we can guess and create meanings. Other life-forms don’t have that ability to create knowledge actively. Our ability comes with a great cost of potentially doing very (infinitely) stupid things.
TheTuringPrincipledevelop

Classical information: possibility of ‘flip’ and ‘copy’develop
Quantum information: impossibility (Heisenberg uncertainty principle) of copying certain information-carrying states and possibility of reversing any transformationdevelop
1-2g2t5a There is no such thing as the ‘same’ instance of a particle at different times - i.e., there is no such thing as speed of ‘one instance’ in the quantum physics (Heisenberg uncertainty principle)
1-2g2t5b The term ‘uncertainty principle’ is doubly misleading because first of all fungibility is a physical fact and not uncertainty of anything, and second of all because it can be derived from more general principle of quantum physics
Also assuming Reversible = Fungible:
1-2g2t5 Because rejoining means being fungible means there is no such thing as which of them has ended up as-at which final instance-positiondevelop
(Marletto p.206)