1-2g2k1 Replication of knowledge is what matters. Not replication per se.

1-2g2b Humans are significant insofar as we can create knowledge
10-2g1e What sets humans apart is our ability to accumulate knowledge by means of language
2-1a5a Evolution doesn’t care about lifetime of each individual gene-meme carrier (its sample is beyond your own experience and any human lifetime)

1-2g2k2 The program (e.g., Roman-numeral system) survives by causing computer (e.g., people) to use them. The former instructs the latter.