8-1c Look for inherently digital-native areas and concepts

“I’m getting the digital equivalent of people being willing to pay huge premiums for Waymo over Uber. It inclines me to think that the human premium for many jobs will not only not be high, but in fact be negative.” – Dwarkesh Patel on LLMs-native tutors

Previous:

• 8-1b Look for places where we’ve taken an offline experience and put it online (physical ⇒ intermediate) but haven’t fundamentally innovated yet (⇒ internet-native)

Next:

• 8-1c1 Potential scenario - Digital frontend + Human backend ⇒ Digital frontend + Digital backend
• 8-1d Look for inherently crypto-native areas and concepts

Related:

• 3-1d4b1 What’s been considered ‘analog’ must be represented digitally, because the distinction is rather arbitrary

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E.g.,

• Latent Space on Isomorphic Labs’ drug design breakthrough (20260212)
  • Stronger gains on antibody interface/CDR-H3 improvements and affinity prediction exceeding physics-based methods
    • <> similar to the verifier and the prover turned on its head via AI (see [this](9-1b0a When you have learned something, the way it exists in your mind is the same as the way it exists in the mind of the inventor))